Description
≥99%
HPLC-verified purity
Nucleoside
Compound class
Molecular Breakdown
AICAR — AMPK activator (Acadesine)
AICAR is a nucleoside (not a peptide) and the original, canonical AMPK activator — often called an “exercise mimetic” in metabolic research. Sold as reference material under the name Acadesine / AICA riboside.
Rx
AICAR
Aliases: Acadesine · AICA riboside · AICA ribonucleoside
A purine nucleoside analog studied in preclinical models as a direct activator of AMP-activated protein kinase (AMPK).
TypeNucleoside / AMPK activator
IUPAC name5-Amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide
FormulaC₉H₁₄N₄O₅
Molar mass258.23 g/mol
CAS2627-69-2
Storage: Lyophilized, store at −20°C, protected from light. Reconstitute with bacteriostatic water; keep reconstituted vials at 2–8°C.
Research Focus — AMPK / Metabolism
AICAR is the reference tool compound for activating AMPK in the lab. It is studied for glucose uptake, fatty-acid oxidation, mitochondrial biogenesis, and endurance (“exercise-mimetic”) research models.
AMPK activationExercise-mimetic modelsGlucose uptakeFatty-acid oxidationEndurance research
Selected Research
Published preclinical literature
Peer-reviewed studies of the compound itself (cell and animal models). They do not describe this product or any human use.
Narkar VA, et al. AMPK and PPARδ agonists are exercise mimetics.
Cell. 2008;134(3):405–415. PMID 18674809 ↗
Citations are provided for scientific reference only and do not constitute claims about this product.
⚠️ For Research Use Only. Sold exclusively as reference material for in-vitro laboratory and educational research. Not evaluated by the FDA; not for human or veterinary use, consumption, diagnosis, treatment, or to prevent any disease. Note: AICAR is prohibited in sport (WADA S4, hormone & metabolic modulators).
